26 Aug2020

Intrinsic activity temporal structure reactivity to behavioural state change with depressive symptom

Intrinsic activity temporal structure reactivity to behavioural state change is correlated with depressive symptoms

Niall W Duncan*, Tzu‐Yu Hsu*, Paul Z Cheng, Hsin‐Yi Wang, Hsin‐Chien Lee, Timothy J Lane

Brain activity is responsive to behavioural context, for example rest or tasks, in normal conditions. In this study, we found the intensity of this brain activity’s responsive level decreased with increasing depressive level in beta frequency oscillation. We also found that the brain activity in beta frequency oscillation was negatively correlated with rumination level. This means that the lack in neural activity reactivity may be associated with a general cognitive inflexibility, which may be resulted from overly engage in self-directed information. This study provides an initial link between intrinsic activity reactivity and psychological features in psychiatric disorders.

Published in European Journal of Neuroscience

Here is the link: https://onlinelibrary.wiley.com/doi/abs/10.1111/ejn.14858